The people in this age group are described to be most ambitious, productive and responsible. The age of these patients ranged within 19 to 66 years, with an average age of From April to April , 68 critical patients with severe organophosphorus poisoning treated in our hospital were enrolled into this study. In addition, hemoperfusion cannot guarantee blood temperature of extracorporeal circulation, so blood coagulation often occurs in the perfusion device. There was no statistically significant association with death and age, lag time, severity of poisoning and duration of ventilation independently. Acute pesticides poisoning in the Krakow. The age of the patients ranged from 17 years to 53 years.
Journal List Medicine Baltimore v. In the present study, the incidence of poisoning was highest during the summer months Acute and chronic manifestations. J Clin Exp Med Most of the patients received PAM within hours of poisoning and required mechanical ventilation for days.
The high mortality in patients ventilated for days tjesis most probably due to the severity of poisoning. Baotou Yi Xue ; Korean J Intern Med ; N Engl J Med.
These patients probably developed lung complications due to prolonged mechanical ventilation. The fatal issue is often related to a delay in diagnosis or an improper management.
In A and E, treatment was started as per the protocol for managing OP poisoning patients in our hospital. Patients requiring ventilatory support were initially put on assist pressure orgaophosphorus mode and subsequently weaned off by synchronised intermittent mandatory ventilation SIMVpressure support PS ventilation.
The financial impact of such therapy, particularly in rural India has been raised as an issue in absence of definite beneficial effect of oximes in OP poisoning. Intensive Care Med ; Acute and chronic manifestations.
Out of 86 patients, 52 The dose of atropine and injection interval were adjusted according to changes in the patient’s condition, and these were adjusted every 5 to 20 minutes, to reach the atropinization status in the shortest possible time and to maintain atropinization.
Clothes were removed and body was washed with soap water. In summary, orhanophosphorus study verifies that hemoperfusion and hemodialysis on the basis of routine treatment can improve the success rate of clinical rescue, and improve the prognosis of patients, which is worthy of clinical popularization and application for treating organophosphorus pesticides poisoning patients with renal insufficiency.
The severity of poisoning was graded according to Dreisbach’s classification [ Appendix 1 ]. Severity of poisoning, lag time and duration of mechanical ventilation. The average dose of PAM required per patient was Poisoninv these 16 patients, 6 patients had moderate and 10 patients had severe poisoning. The mode of poisoning was suicidal in 79 Respiratory failure of acute organophosphate and carbamate poisoning.
Severity of poisoning, lag time and duration of mechanical ventilation. Similarly, in the study by Srinivas et al. According to Kumar et al.
Patients in the treatment group additionally received hemoperfusion and hemodialysis on the basis of routine emergency treatment. Follow-up study of delayed damage caused by acute organophosphorus pesticide poisoning. Though the odds of death due to OP poisoning given presence of age, lag time, severity of poisoning and organiphosphorus of mechanical ventilation were statistically insignificant, but the odds ratio OR more than 1 in all these cases show exposure associated with higher odds of outcome [ Table 5 ].
Meanwhile, organic pesticide has a strong lipid solubility, which leads to central respiratory failure through blood—brain barrier. Furthermore, regular drugs are unable to effectively eliminate inflammatory medium formed in the poisoning process, metabolites caused by organ damage or organophosphorus pesticide in the body.
Count data were evaluated using Chi-square test. Analysis of the prognosis of 30 cases with multiple organ dysfunction syndrome MODS caused by acute organophosphorus poisoning. Intensive care management of organophosphate insecticide poisoning. However, as a principle, treatment of OP poisoning should be started immediately and must not await the results for serum cholinesterase levels. The vital signs piisoning patients were closely monitored during the course of treatment.
In this study, the cholinesterase levels were not assessed due to non-availability of the facility.